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Sulfadiazine sodium is a sulfonamide antibiotic with antimalarial activity, primarily used for toxoplasmosis research. It presents as a white to off-white solid.
Functions as a sulfonamide antibiotic
Exhibits antimalarial activity
Utilized in toxoplasmosis research
Demonstrates effectiveness against specific T. gondii strains
Appears as a white to off-white solid
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Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid It serves as an intermediate for the preparation of 26-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid
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Sulfathiazole is an orally active compound identified as an endocrine disruptor. It specifically targets the steroidogenic pathway by enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and increasing the mRNA expression of CYP17, CYP19, and 3β-HSD. This leads to an increased production of 17-estradiol (E2) and has been observed to cause endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish.
Orally active.
Targets the steroidogenic pathway.
Enhances CYP19 activity in human adrenal cancer cells (H295R).
Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD.
Increases 17-estradiol (E2) production.
Exhibits endocrine disrupting effects on aquatic organisms (e.g., Japanese medaka fish).
Can inhibit the corrosion of copper in 0.1 M NaCl solution, with efficiency exceeding 80% at increased concentrations.
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Sulfapyridine is a sulfonamide antibiotic agent and a significant metabolite of Sulfasalazine. It exhibits antibacterial, anti-inflammatory, and anti-rheumatic activities by inhibiting recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM.
Inhibits production of IL-8, CXCL1, and MCP-1 in synovial cells.
Effective against Y. enterocolitica and Salmonella.
Significantly inhibits systemic allergic reactions in rats.
Molecular weight: 249.29.
Chemical formula: C11H11N3O2S.
Appearance: white to off-white solid.
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Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM. Other sizes are also available. Please inqury us for quote.
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Sodium Sulfadiazine (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine an intermediate-acting bacteriostatic synthetic sulfanilamide derivative
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